{
  "publisher": "Aero Clinic",
  "url": "https://www.cagri.co.uk/glossary",
  "terms": [
    {
      "term": "BMI",
      "definition": "Body mass index. Your weight in kilograms divided by your height in metres squared. Prescribers use BMI as one of the checks for treatment.",
      "url": "https://www.cagri.co.uk/glossary#term-bmi",
      "see_also": "https://www.cagri.co.uk/bmi-calculator"
    },
    {
      "term": "Calorie deficit",
      "definition": "Eating fewer calories than your body uses. A deficit is needed for fat loss.",
      "url": "https://www.cagri.co.uk/glossary#term-calorie-deficit",
      "see_also": "https://www.cagri.co.uk/calorie-calculator"
    },
    {
      "term": "Check-in",
      "definition": "A short monthly form about your weight, side effects and how you feel. A prescriber reads each check-in before your next supply.",
      "url": "https://www.cagri.co.uk/glossary#term-check-in",
      "see_also": "https://www.cagri.co.uk/how-it-works"
    },
    {
      "term": "Cold chain",
      "definition": "Chilled packaging and fast delivery used to keep injection pens between 2 and 8 degrees C in transit.",
      "url": "https://www.cagri.co.uk/glossary#term-cold-chain",
      "see_also": "https://www.cagri.co.uk/delivery"
    },
    {
      "term": "Dose step",
      "definition": "One level in a dose schedule. You stay on each step for a set minimum time before moving up.",
      "url": "https://www.cagri.co.uk/glossary#term-dose-step",
      "see_also": "https://www.cagri.co.uk/mounjaro-doses"
    },
    {
      "term": "Efficacy estimand",
      "definition": "A trial result estimating the effect in people who stayed on the medicine. This figure is always higher than the result counting everyone.",
      "url": "https://www.cagri.co.uk/glossary#term-efficacy-estimand",
      "see_also": "https://www.cagri.co.uk/clinical-evidence"
    },
    {
      "term": "Food noise",
      "definition": "Constant thoughts about food. Many people report less food noise on GLP-1 medicines.",
      "url": "https://www.cagri.co.uk/glossary#term-food-noise",
      "see_also": "https://www.cagri.co.uk/emotional-eating"
    },
    {
      "term": "Foundayo",
      "definition": "The brand name for orforglipron tablets, taken once a day. Made by Eli Lilly.",
      "url": "https://www.cagri.co.uk/glossary#term-foundayo",
      "see_also": "https://www.cagri.co.uk/foundayo"
    },
    {
      "term": "Gallstones",
      "definition": "Small stones which form in the gallbladder. Rapid weight loss from any cause raises the risk.",
      "url": "https://www.cagri.co.uk/glossary#term-gallstones",
      "see_also": "https://www.cagri.co.uk/gallstones"
    },
    {
      "term": "Gastric emptying",
      "definition": "The speed at which food leaves your stomach. GLP-1 medicines slow gastric emptying, so you feel full for longer.",
      "url": "https://www.cagri.co.uk/glossary#term-gastric-emptying",
      "see_also": "https://www.cagri.co.uk/what-is-glp1"
    },
    {
      "term": "GIP",
      "definition": "Glucose-dependent insulinotropic polypeptide. A gut hormone involved in appetite and blood sugar. Mounjaro acts on GIP and GLP-1 receptors.",
      "url": "https://www.cagri.co.uk/glossary#term-gip",
      "see_also": "https://www.cagri.co.uk/how-weight-loss-injections-work"
    },
    {
      "term": "GLP-1",
      "definition": "Glucagon-like peptide-1. A gut hormone released after eating. GLP-1 tells your brain you are full and helps control blood sugar.",
      "url": "https://www.cagri.co.uk/glossary#term-glp-1",
      "see_also": "https://www.cagri.co.uk/what-is-glp1"
    },
    {
      "term": "GLP-1 receptor agonist",
      "definition": "A medicine which acts on the same receptor as the GLP-1 hormone. Wegovy, the Wegovy pill and Foundayo belong to this group.",
      "url": "https://www.cagri.co.uk/glossary#term-glp-1-receptor-agonist",
      "see_also": "https://www.cagri.co.uk/what-is-glp1"
    },
    {
      "term": "GMC",
      "definition": "General Medical Council. The regulator for doctors in the UK.",
      "url": "https://www.cagri.co.uk/glossary#term-gmc",
      "see_also": "https://www.cagri.co.uk/safety"
    },
    {
      "term": "GPhC",
      "definition": "General Pharmaceutical Council. The regulator for pharmacies, pharmacists and pharmacy technicians in Great Britain.",
      "url": "https://www.cagri.co.uk/glossary#term-gphc",
      "see_also": "https://www.cagri.co.uk/safety"
    },
    {
      "term": "Health check",
      "definition": "The online questionnaire about your health, medicines and weight. A prescriber reviews your answers before any prescription.",
      "url": "https://www.cagri.co.uk/glossary#term-health-check",
      "see_also": "https://www.cagri.co.uk/how-it-works"
    },
    {
      "term": "Hypoglycaemia",
      "definition": "Low blood sugar. The risk rises when a GLP-1 medicine is combined with insulin or a sulfonylurea.",
      "url": "https://www.cagri.co.uk/glossary#term-hypoglycaemia",
      "see_also": "https://www.cagri.co.uk/glp1-and-diabetes"
    },
    {
      "term": "Independent prescriber",
      "definition": "A pharmacist or nurse with an extra qualification allowing them to prescribe medicines.",
      "url": "https://www.cagri.co.uk/glossary#term-independent-prescriber",
      "see_also": "https://www.cagri.co.uk/clinical-team"
    },
    {
      "term": "Integrated care board",
      "definition": "An NHS body planning health services for a local area in England. Each board sets local access to NHS weight management.",
      "url": "https://www.cagri.co.uk/glossary#term-integrated-care-board",
      "see_also": "https://www.cagri.co.uk/weight-loss-treatment-on-the-nhs"
    },
    {
      "term": "KwikPen",
      "definition": "The multi-dose injection pen used for Mounjaro. One pen holds four weekly doses.",
      "url": "https://www.cagri.co.uk/glossary#term-kwikpen",
      "see_also": "https://www.cagri.co.uk/injection-technique"
    },
    {
      "term": "Lean mass",
      "definition": "Everything in your body other than fat, including muscle. Protein and resistance training help protect lean mass during weight loss.",
      "url": "https://www.cagri.co.uk/glossary#term-lean-mass",
      "see_also": "https://www.cagri.co.uk/muscle-loss"
    },
    {
      "term": "Licence",
      "definition": "Approval from the medicines regulator to market a medicine for a stated use. The licence sets the doses and who can take the medicine.",
      "url": "https://www.cagri.co.uk/glossary#term-licence",
      "see_also": "https://www.cagri.co.uk/safety"
    },
    {
      "term": "Liraglutide",
      "definition": "A daily GLP-1 injection. Nevolat is one brand.",
      "url": "https://www.cagri.co.uk/glossary#term-liraglutide",
      "see_also": "https://www.cagri.co.uk/nevolat"
    },
    {
      "term": "Maintenance dose",
      "definition": "The dose you stay on once weight loss and side effects are in balance.",
      "url": "https://www.cagri.co.uk/glossary#term-maintenance-dose",
      "see_also": "https://www.cagri.co.uk/maintenance-doses"
    },
    {
      "term": "MHRA",
      "definition": "Medicines and Healthcare products Regulatory Agency. The UK regulator for medicines and medical devices.",
      "url": "https://www.cagri.co.uk/glossary#term-mhra",
      "see_also": "https://www.cagri.co.uk/safety"
    },
    {
      "term": "Mounjaro",
      "definition": "The brand name for tirzepatide, a weekly injection. Made by Eli Lilly.",
      "url": "https://www.cagri.co.uk/glossary#term-mounjaro",
      "see_also": "https://www.cagri.co.uk/mounjaro"
    },
    {
      "term": "NICE",
      "definition": "National Institute for Health and Care Excellence. NICE writes guidance on which treatments the NHS in England should offer.",
      "url": "https://www.cagri.co.uk/glossary#term-nice",
      "see_also": "https://www.cagri.co.uk/weight-loss-treatment-on-the-nhs"
    },
    {
      "term": "Off-licence use",
      "definition": "Using a medicine in a way the licence does not cover, such as a different dose gap. Only a prescriber can decide this.",
      "url": "https://www.cagri.co.uk/glossary#term-off-licence-use",
      "see_also": "https://www.cagri.co.uk/maintenance-doses"
    },
    {
      "term": "Oral semaglutide",
      "definition": "Semaglutide in tablet form. The Wegovy pill is the version licensed for weight management.",
      "url": "https://www.cagri.co.uk/glossary#term-oral-semaglutide",
      "see_also": "https://www.cagri.co.uk/wegovy-tablets"
    },
    {
      "term": "Orforglipron",
      "definition": "The active ingredient in Foundayo. A GLP-1 medicine taken as a daily tablet with no food or water rules.",
      "url": "https://www.cagri.co.uk/glossary#term-orforglipron",
      "see_also": "https://www.cagri.co.uk/foundayo"
    },
    {
      "term": "Orlistat",
      "definition": "A capsule taken with meals. Orlistat reduces the fat your gut absorbs.",
      "url": "https://www.cagri.co.uk/glossary#term-orlistat",
      "see_also": "https://www.cagri.co.uk/orlistat"
    },
    {
      "term": "Pancreatitis",
      "definition": "Inflammation of the pancreas. The main sign is severe stomach pain which does not ease. This needs emergency care.",
      "url": "https://www.cagri.co.uk/glossary#term-pancreatitis",
      "see_also": "https://www.cagri.co.uk/urgent-help"
    },
    {
      "term": "Patient information leaflet",
      "definition": "The leaflet inside every medicine pack. The leaflet explains how to take the medicine and lists side effects.",
      "url": "https://www.cagri.co.uk/glossary#term-patient-information-leaflet",
      "see_also": "https://www.cagri.co.uk/weight-loss-medicine-safety"
    },
    {
      "term": "Placebo",
      "definition": "A dummy treatment with no active ingredient. Trials compare a medicine against placebo to measure the true effect.",
      "url": "https://www.cagri.co.uk/glossary#term-placebo",
      "see_also": "https://www.cagri.co.uk/clinical-evidence"
    },
    {
      "term": "Plateau",
      "definition": "A stretch of several weeks with no weight change despite steady habits.",
      "url": "https://www.cagri.co.uk/glossary#term-plateau",
      "see_also": "https://www.cagri.co.uk/weight-loss-plateau"
    },
    {
      "term": "Prediabetes",
      "definition": "Blood sugar above the normal range but below the range for type 2 diabetes.",
      "url": "https://www.cagri.co.uk/glossary#term-prediabetes",
      "see_also": "https://www.cagri.co.uk/glp1-and-diabetes"
    },
    {
      "term": "Prescriber",
      "definition": "A clinician with the legal right to prescribe medicines, such as a doctor or an independent prescriber.",
      "url": "https://www.cagri.co.uk/glossary#term-prescriber",
      "see_also": "https://www.cagri.co.uk/clinical-team"
    },
    {
      "term": "Prescription only medicine",
      "definition": "A medicine you can get only with a prescription from a qualified prescriber. Often shortened to POM.",
      "url": "https://www.cagri.co.uk/glossary#term-prescription-only-medicine",
      "see_also": "https://www.cagri.co.uk/safety"
    },
    {
      "term": "Randomised controlled trial",
      "definition": "A study where people are assigned by chance to a treatment or a comparison group. This design gives the most reliable evidence.",
      "url": "https://www.cagri.co.uk/glossary#term-randomised-controlled-trial",
      "see_also": "https://www.cagri.co.uk/clinical-evidence"
    },
    {
      "term": "Semaglutide",
      "definition": "The active ingredient in Wegovy and the Wegovy pill. Made by Novo Nordisk.",
      "url": "https://www.cagri.co.uk/glossary#term-semaglutide",
      "see_also": "https://www.cagri.co.uk/wegovy"
    },
    {
      "term": "Sharps bin",
      "definition": "A rigid container for used needles and pens.",
      "url": "https://www.cagri.co.uk/glossary#term-sharps-bin",
      "see_also": "https://www.cagri.co.uk/injection-technique"
    },
    {
      "term": "SmPC",
      "definition": "Summary of product characteristics. The official document for clinicians describing how a medicine is used, with trial data and side effect rates.",
      "url": "https://www.cagri.co.uk/glossary#term-smpc",
      "see_also": "https://www.cagri.co.uk/clinical-evidence"
    },
    {
      "term": "Starter dose",
      "definition": "The first and lowest dose. The starter dose lets your body adjust before the dose rises.",
      "url": "https://www.cagri.co.uk/glossary#term-starter-dose",
      "see_also": "https://www.cagri.co.uk/first-month-mounjaro"
    },
    {
      "term": "Subcutaneous injection",
      "definition": "An injection into the fat layer under the skin of your stomach, thigh or upper arm.",
      "url": "https://www.cagri.co.uk/glossary#term-subcutaneous-injection",
      "see_also": "https://www.cagri.co.uk/injection-technique"
    },
    {
      "term": "Superintendent pharmacist",
      "definition": "The pharmacist accountable for the safe running of pharmacy services across a pharmacy company.",
      "url": "https://www.cagri.co.uk/glossary#term-superintendent-pharmacist",
      "see_also": "https://www.cagri.co.uk/clinical-team"
    },
    {
      "term": "Tapering",
      "definition": "Lowering a dose in steps before stopping.",
      "url": "https://www.cagri.co.uk/glossary#term-tapering",
      "see_also": "https://www.cagri.co.uk/tapering-off-glp1"
    },
    {
      "term": "Tirzepatide",
      "definition": "The active ingredient in Mounjaro. Tirzepatide acts on both GIP and GLP-1 receptors.",
      "url": "https://www.cagri.co.uk/glossary#term-tirzepatide",
      "see_also": "https://www.cagri.co.uk/mounjaro"
    },
    {
      "term": "Titration",
      "definition": "Raising a dose in planned steps to limit side effects.",
      "url": "https://www.cagri.co.uk/glossary#term-titration",
      "see_also": "https://www.cagri.co.uk/mounjaro-doses"
    },
    {
      "term": "Treatment-regimen estimand",
      "definition": "A trial result counting everyone who started, including people who stopped the medicine early. We quote this figure first on every page.",
      "url": "https://www.cagri.co.uk/glossary#term-treatment-regimen-estimand",
      "see_also": "https://www.cagri.co.uk/clinical-evidence"
    },
    {
      "term": "Type 2 diabetes",
      "definition": "A condition where blood sugar stays too high because insulin does not work well enough.",
      "url": "https://www.cagri.co.uk/glossary#term-type-2-diabetes",
      "see_also": "https://www.cagri.co.uk/glp1-and-diabetes"
    },
    {
      "term": "Wegovy",
      "definition": "The brand name for semaglutide for weight management. Available as a weekly pen and a daily tablet. Made by Novo Nordisk.",
      "url": "https://www.cagri.co.uk/glossary#term-wegovy",
      "see_also": "https://www.cagri.co.uk/wegovy"
    },
    {
      "term": "Weight-related condition",
      "definition": "A health problem linked to excess weight, such as high blood pressure, prediabetes or sleep apnoea. One such condition lowers the BMI threshold for treatment to 27.",
      "url": "https://www.cagri.co.uk/glossary#term-weight-related-condition",
      "see_also": "https://www.cagri.co.uk/eligibility"
    },
    {
      "term": "Weight regain",
      "definition": "Weight returning after treatment stops. A maintenance plan lowers the risk.",
      "url": "https://www.cagri.co.uk/glossary#term-weight-regain",
      "see_also": "https://www.cagri.co.uk/preventing-weight-regain"
    },
    {
      "term": "Yellow Card",
      "definition": "The MHRA scheme for reporting suspected side effects of medicines.",
      "url": "https://www.cagri.co.uk/glossary#term-yellow-card",
      "see_also": "https://www.cagri.co.uk/urgent-help"
    }
  ],
  "clinical_review_status": "pending",
  "source_content_date": "2026-10-15"
}