Switching weight loss treatments

The golden rules #

• Never overlap. Two GLP-1 medicines at once multiply side effects without doubling benefit.
• Start lower than the conversion suggests. Tolerance does not transfer perfectly between molecules. Moving from Wegovy 2.4 mg does not mean starting Mounjaro at 10 mg.
• Time the switch at a dose boundary. The cleanest moment is when a pen or pack runs out.
• Bring your history. Your previous doses, side effects and results shape the new starting point.

Switching to Mounjaro #

From Wegovy or a tablet, everyone starts Mounjaro at 2.5 mg, even from high semaglutide doses. The GIP component is new to your body and needs a separate adjustment month. Most people then titrate faster than a brand-new patient, stepping up every 4 weeks until appetite control matches what they had before.

Switching to Wegovy #

From Mounjaro, prescribers usually start Wegovy at 0.5 mg or 1 mg depending on your previous dose and tolerance, not the full 0.25 mg restart, but not a direct conversion either. From Wegovy tablets to the pen (or back), the molecule is identical, so the mapping is closer to one-to-one.

Switching to daily tablets #

A common maintenance move. From a weekly pen, you start the tablet the day after your next injection would have been due, at a low dose, stepping up monthly. The daily ritual replaces the weekly one with no gap in coverage.

Switching provider to Aero Clinic #

Already on treatment elsewhere? Bring proof of your current dose, a photo of your pen or pack, or a pharmacy record. We continue your titration and do not restart from the beginning, subject to the prescriber's review of your history.