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Weight loss treatment glossary

54 terms you meet during treatment, each explained in one or two sentences. Every entry links to a guide with more detail.

B

BMI
Body mass index. Your weight in kilograms divided by your height in metres squared. Prescribers use BMI as one of the checks for treatment. BMI calculator

C

Calorie deficit
Eating fewer calories than your body uses. A deficit is needed for fat loss. Calorie calculator
Check-in
A short monthly form about your weight, side effects and how you feel. A prescriber reads each check-in before your next supply. How Aero Clinic works
Cold chain
Chilled packaging and fast delivery used to keep injection pens between 2 and 8 degrees C in transit. Delivery and packaging

D

Dose step
One level in a dose schedule. You stay on each step for a set minimum time before moving up. Mounjaro doses

E

Efficacy estimand
A trial result estimating the effect in people who stayed on the medicine. This figure is always higher than the result counting everyone. Clinical evidence

F

Food noise
Constant thoughts about food. Many people report less food noise on GLP-1 medicines. Emotional eating
Foundayo
The brand name for orforglipron tablets, taken once a day. Made by Eli Lilly. Read more

G

Gallstones
Small stones which form in the gallbladder. Rapid weight loss from any cause raises the risk. GLP-1 and gallstones
Gastric emptying
The speed at which food leaves your stomach. GLP-1 medicines slow gastric emptying, so you feel full for longer. What is a GLP-1 medicine?
GIP
Glucose-dependent insulinotropic polypeptide. A gut hormone involved in appetite and blood sugar. Mounjaro acts on GIP and GLP-1 receptors. How weight loss injections and pills work
GLP-1
Glucagon-like peptide-1. A gut hormone released after eating. GLP-1 tells your brain you are full and helps control blood sugar. What is a GLP-1 medicine?
GLP-1 receptor agonist
A medicine which acts on the same receptor as the GLP-1 hormone. Wegovy, the Wegovy pill and Foundayo belong to this group. What is a GLP-1 medicine?
GMC
General Medical Council. The regulator for doctors in the UK. Safety and regulation
GPhC
General Pharmaceutical Council. The regulator for pharmacies, pharmacists and pharmacy technicians in Great Britain. Safety and regulation

H

Health check
The online questionnaire about your health, medicines and weight. A prescriber reviews your answers before any prescription. How Aero Clinic works
Hypoglycaemia
Low blood sugar. The risk rises when a GLP-1 medicine is combined with insulin or a sulfonylurea. GLP-1 and type 2 diabetes

I

Independent prescriber
A pharmacist or nurse with an extra qualification allowing them to prescribe medicines. Clinical team
Integrated care board
An NHS body planning health services for a local area in England. Each board sets local access to NHS weight management. Weight loss treatment on the NHS

K

KwikPen
The multi-dose injection pen used for Mounjaro. One pen holds four weekly doses. Injection technique

L

Lean mass
Everything in your body other than fat, including muscle. Protein and resistance training help protect lean mass during weight loss. Muscle loss: prevention
Licence
Approval from the medicines regulator to market a medicine for a stated use. The licence sets the doses and who can take the medicine. Safety and regulation
Liraglutide
A daily GLP-1 injection. Nevolat is one brand. Nevolat

M

Maintenance dose
The dose you stay on once weight loss and side effects are in balance. Maintenance doses explained
MHRA
Medicines and Healthcare products Regulatory Agency. The UK regulator for medicines and medical devices. Safety and regulation
Mounjaro
The brand name for tirzepatide, a weekly injection. Made by Eli Lilly. Read more

N

NICE
National Institute for Health and Care Excellence. NICE writes guidance on which treatments the NHS in England should offer. Weight loss treatment on the NHS

O

Off-licence use
Using a medicine in a way the licence does not cover, such as a different dose gap. Only a prescriber can decide this. Maintenance doses explained
Oral semaglutide
Semaglutide in tablet form. The Wegovy pill is the version licensed for weight management. Read more
Orforglipron
The active ingredient in Foundayo. A GLP-1 medicine taken as a daily tablet with no food or water rules. Read more
Orlistat
A capsule taken with meals. Orlistat reduces the fat your gut absorbs. Orlistat

P

Pancreatitis
Inflammation of the pancreas. The main sign is severe stomach pain which does not ease. This needs emergency care. Urgent help
Patient information leaflet
The leaflet inside every medicine pack. The leaflet explains how to take the medicine and lists side effects. Weight loss medicine safety
Placebo
A dummy treatment with no active ingredient. Trials compare a medicine against placebo to measure the true effect. Clinical evidence
Plateau
A stretch of several weeks with no weight change despite steady habits. Breaking a plateau
Prediabetes
Blood sugar above the normal range but below the range for type 2 diabetes. GLP-1 and type 2 diabetes
Prescriber
A clinician with the legal right to prescribe medicines, such as a doctor or an independent prescriber. Clinical team
Prescription only medicine
A medicine you can get only with a prescription from a qualified prescriber. Often shortened to POM. Safety and regulation

R

Randomised controlled trial
A study where people are assigned by chance to a treatment or a comparison group. This design gives the most reliable evidence. Clinical evidence

S

Semaglutide
The active ingredient in Wegovy and the Wegovy pill. Made by Novo Nordisk. Read more
Sharps bin
A rigid container for used needles and pens. Injection technique
SmPC
Summary of product characteristics. The official document for clinicians describing how a medicine is used, with trial data and side effect rates. Clinical evidence
Starter dose
The first and lowest dose. The starter dose lets your body adjust before the dose rises. Your first month on Mounjaro
Subcutaneous injection
An injection into the fat layer under the skin of your stomach, thigh or upper arm. Injection technique
Superintendent pharmacist
The pharmacist accountable for the safe running of pharmacy services across a pharmacy company. Clinical team

T

Tapering
Lowering a dose in steps before stopping. Tapering off GLP-1 treatment
Tirzepatide
The active ingredient in Mounjaro. Tirzepatide acts on both GIP and GLP-1 receptors. Read more
Titration
Raising a dose in planned steps to limit side effects. Mounjaro doses
Treatment-regimen estimand
A trial result counting everyone who started, including people who stopped the medicine early. We quote this figure first on every page. Clinical evidence
Type 2 diabetes
A condition where blood sugar stays too high because insulin does not work well enough. GLP-1 and type 2 diabetes

W

Wegovy
The brand name for semaglutide for weight management. Available as a weekly pen and a daily tablet. Made by Novo Nordisk. Read more
Weight regain
Weight returning after treatment stops. A maintenance plan lowers the risk. Preventing weight regain

Y

Yellow Card
The MHRA scheme for reporting suspected side effects of medicines. Urgent help

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Page information

Summary
Plain English definitions for 54 weight loss treatment terms, from BMI and GLP-1 to titration, maintenance dose and Yellow Card. Explore the full guide.
Publisher
Aero Clinic, operated by AERO HEALTHCARE LTD.
Editorial update
Clinical review
Pending. An editorial update is not a clinical sign-off.

Cite as: Weight loss treatment glossary, Aero Clinic (https://www.cagri.co.uk), AERO HEALTHCARE LTD. https://www.cagri.co.uk/glossary. Editorial update: 4 November 2026. Clinical review pending.

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