Daily tablet, oral semaglutide
Wegovy pill for weight loss
The Wegovy pill is a daily semaglutide tablet. You get the same medicine as the Wegovy pen with no needle. Take one tablet each morning on an empty stomach.
Prices to be confirmed
Starter dose, first month
Start with the Wegovy pillThe planned service requires a clinical assessment before any treatment can be supplied. The secure assessment is not connected in this preview. Read how assessment works or prepare a discussion checklist. Provider details, prices and delivery arrangements must be confirmed before launch.
- UK prescriber review
- Dispensing arrangements to be confirmed
- Delivery arrangements to be confirmed
In short: the Wegovy pill (oral semaglutide) is a once-daily tablet in four doses: 1.5 mg, 4 mg, 9 mg and 25 mg. Average weight loss was 13.6% at 64 weeks on 25 mg in the OASIS 4 trial. Aero’s prices are not yet confirmed.
How the Wegovy pill works
Oral semaglutide is the same molecule as the Wegovy pen. The tablet includes an absorption enhancer, so the medicine survives the stomach and enters the bloodstream.
In the OASIS 4 trial, the 25 mg tablet produced an average loss of 13.6% over 64 weeks, against 2.2% with placebo. The 2.4 mg pen averaged 14.9% over 68 weeks in a separate trial.
Side effects match the pen: nausea, constipation, reflux and tiredness, with similar rates in trials. Read the side effects guide.
Wegovy pill doses and prices
Tablets follow the same approach as the pen. Start at 1.5 mg, then 4 mg, 9 mg and 25 mg. Each step lasts at least 1 month, and you move up only if the current dose is tolerated.
| Dose | Price a month | Stage | Price per tablet |
|---|---|---|---|
| 1.5 mg | To be confirmed | Starter dose, first month | To be confirmed |
| 4 mg | To be confirmed | Step 2 | To be confirmed |
| 9 mg | To be confirmed | Step 3 | To be confirmed |
| 25 mg | To be confirmed | Maintenance dose | To be confirmed |
Missed a tablet? Skip the missed tablet and take the next one at the usual time the following morning. Never take two to catch up.
What the trials found
OASIS 4 tested oral semaglutide 25 mg in 307 adults for 64 weeks, alongside diet and activity support.
13.6%
average weight loss, counting every participant. The placebo group averaged 2.2%.
Other trials
- OASIS 1 (50 mg, not a UK licensed dose). 667 adults with overweight or obesity without type 2 diabetes, 68 weeks. Mean weight change was -15.1% with oral semaglutide 50 mg and -2.4% with placebo. 85% versus 26% lost at least 5%, 69% versus 12% at least 10%, 54% versus 6% at least 15% and 34% versus 3% at least 20%. Gastrointestinal adverse events occurred in 80% versus 46%.
Side effect rates in trials
| Effect | Rate | Dose |
|---|---|---|
| Nausea | 46.6% | 25 mg |
| Vomiting | 30.9% | 25 mg |
| Constipation | 20.1% | 25 mg |
| Diarrhoea | 17.6% | 25 mg |
| Hair loss | 6.4% | 25 mg |
| Dysaesthesia (altered skin sensation) | 4.9% | 25 mg |
| Any gastrointestinal adverse event | 74% | 25 mg |
| Stopped treatment because of a gastrointestinal event | 3.4% | 25 mg |
Main trial: Wharton S, Lingvay I, Bogdanski P, et al. Oral Semaglutide at a Dose of 25 mg in Adults with Overweight or Obesity. N Engl J Med 2025, 393(11):1077-1087. Individual results vary, and no result is promised.
Questions about support for the Wegovy pill
Aero’s treatment prices and service inclusions will be confirmed before booking opens. Ask which prescribing, dispensing, delivery and follow-up costs are included in your quote.
- Before treatment begins, the prescribing clinician’s identity and professional registration must be clear. Aero’s named prescriber details will be published before booking opens.
- Agree a follow-up schedule with your prescriber, including how you report progress and side effects and who decides whether a dose should change.
Ask how to contact your clinical team
Questions about side effects, injecting or travel go to the pharmacy team who dispense your medicine. Clinical support hours and response times will be confirmed before the service launches.
What support includesSide effect help when you need help
You get practical steps for nausea, constipation and reflux, plus the warning signs needing urgent care.
Side effects and problemsFood, movement and sleep guidance
Nine guides cover protein, hydration, exercise and sleep, so you keep muscle while you lose weight.
Read the guides- Ask how maintenance care will be reviewed and priced. Aero’s longer-term service arrangements will be confirmed before booking opens.
How to take the Wegovy pill
- 1
Empty stomach
Take your tablet first thing, before food or drink.
- 2
Small sip of water
Swallow the tablet whole with no more than half a glass of water, about 120 ml. Do not split, crush or chew.
- 3
Wait 30 minutes
Wait at least 30 minutes before eating, drinking anything else, or taking other medicines.
- 4
Same time daily
Most people anchor the tablet to waking up: tablet, then shower, then breakfast.
Side effects and safety
Why people choose the tablet
No needles and no sharps bin. Room-temperature storage means no fridge space and easier travel. A blister pack draws no attention.
Get urgent help
Severe stomach pain reaching your back, swelling of the face or throat, trouble breathing, or vomiting so severe you keep no fluids down. Call 999 or go to A&E. For other concerns call 111.
If the routine feels hard
The weekly Wegovy pen or the Foundayo pill, with no fasting rule, may suit you better. Your prescriber can switch your plan.
Report any suspected side effect through the MHRA Yellow Card scheme. Read the patient leaflet in your pack before your first dose.
Safety information for all four medicinesWhen to get urgent help
Who can start the Wegovy pill
Your prescriber makes the final decision after your health check.
Usually suitable
- Aged 18 to 75
- BMI of 30 or above
- BMI of 27 or above with a weight-related condition, such as high blood pressure
- Lower BMI thresholds can apply for some ethnic backgrounds
Not suitable
- Pregnant, breastfeeding or trying to conceive
- History of pancreatitis
- Personal or family history of medullary thyroid cancer or MEN2
- Type 1 diabetes, or a current eating disorder
Wegovy pill key facts
The main points from the UK product information and the main trial, in one table.
| Detail | Information |
|---|---|
| Active ingredient | Oral semaglutide |
| Medicine type | GLP-1 receptor agonist |
| Made by | Novo Nordisk |
| Form | Tablet |
| How often | Once daily |
| Dose range | 1.5 mg to 25 mg |
| Dose steps | 4 doses, at least 1 month each |
| Highest dose | 25 mg once daily |
| Main trial | OASIS 4, 307 people, 64 weeks |
| Average loss in the main trial | 13.6% on 25 mg, against 2.2% on placebo |
| Storage | No special temperature. Keep in the blister |
| Missed dose | Skip, take the next tablet tomorrow |
| The contraceptive pill | No clinically relevant effect reported |
| Stop before a planned pregnancy | At least 2 months |
| Legal status | Prescription only medicine |
| On the NHS | Not available on the NHS |
| Price at Aero Clinic | To be confirmed |
Wegovy pill questions
How much does the Wegovy pill cost?
Aero’s treatment prices are not yet confirmed. Before paying, ask for the total price, pack quantity, prescribing fees, dispensing and delivery charges, and follow-up costs. Use your provider’s written quote in the cost planner.
Are the tablets as effective as the pen?
The results are close. In OASIS 4, the 25 mg tablet averaged 13.6% loss at 64 weeks. In STEP 1, the 2.4 mg pen averaged 14.9% at 68 weeks. These were separate trials. The daily routine is the trade-off for going needle-free.
What if I forget a tablet?
Skip the missed tablet and resume your usual dose the next day. Do not take an extra tablet to make up for it. Check the patient leaflet and ask your pharmacist if you are unsure.
Can I switch between the pen and tablets?
A switch needs a prescriber’s instructions for your current treatment and dose. Tablets and injections are not interchangeable milligram for milligram. Our tablets and pen comparison explains practical differences; ask your clinician to confirm the changeover plan.
Wegovy pill guides
Other plans
Clinical governance
Awaiting clinical provider details
The dispensing pharmacy, GPhC registration number and Superintendent Pharmacist will be named here once confirmed. A UK prescriber reviews every order before any medicine is supplied.
Page information
- Summary
- Information about oral semaglutide for weight management, including treatment routines, evidence, risks and questions for a prescriber. See the full guide.
- Publisher
- Aero Clinic, operated by AERO HEALTHCARE LTD.
- Editorial update
- Clinical review
- Pending. An editorial update is not a clinical sign-off.
Cite as: Wegovy pill for weight loss, Aero Clinic (https://www.cagri.co.uk), AERO HEALTHCARE LTD. https://www.cagri.co.uk/wegovy-tablets. Editorial update: 4 November 2026. Clinical review pending.