Your first month on Wegovy: week by week
The 0.25 mg starter month is deliberately gentle. What each week feels like, and what to ignore.
Week 1: the first dose #
The 0.25 mg starter dose is sub-therapeutic. The job of this dose is adjustment. Expect little appetite change and possibly mild nausea in the first couple of days. The pen routine is the main week-one win. Choose your day and learn the clicks.
Week 2: subtle shifts #
Fullness arrives a little earlier. Some people notice nothing at all and worry the medicine is not working. This is normal. The working doses begin at 0.5 mg and above.
Week 3: habits worth building now #
Whatever the scales say, this is the week to install the maintenance habits: protein first at meals, steady fluids, a daily walk. People who build these on a quiet month have them ready when loss accelerates.
Week 4: the check-in #
Your check-in weighs the month: weight trend, side effects, how eating feels. Most people step up to 0.5 mg. Some hold. Both are correct answers in the right circumstances.
Setting month-one expectations #
Typical first-month loss is 2 to 3% of body weight. STEP 1's headline average of about 15% took 68 weeks. Pace yourself against this longer timeline, not against week two.
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Page information
- Summary
- What the first month on Wegovy feels like, week by week: the 0.25 mg starter dose, appetite changes, side effects and realistic expectations.
- Publisher
- Aero Clinic, operated by AERO HEALTHCARE LTD.
- Editorial update
- Clinical review
- Pending. An editorial update is not a clinical sign-off.
Cite as: Your first month on Wegovy: week by week, Aero Clinic (https://www.cagri.co.uk), AERO HEALTHCARE LTD. https://www.cagri.co.uk/first-month-wegovy. Editorial update: 4 November 2026. Clinical review pending.